Estrogen receptor thymine-adenine dinucleotide repeat polymorphism is associated with susceptibility to leiomyoma.

doi:10.1016/s0015-0282(02)04563-6

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Article

Estrogen receptor thymine-adenine dinucleotide repeat polymorphism is associated with susceptibility to leiomyoma.

Fertility and sterility - 1 Jan 2003

Hsieh Yao-Yuan, Chang Chi-Chen, Tsai Fuu-Jen, Tsai Horng-Der, Yeh Lian-Shun, Lin Cheng-Chieh, Tsai Chang-Hai

Abstract excerpt

OBJECTIVE: To evaluate the association between leiomyomas and estrogen receptor gene polymorphism. DESIGN: Prospective study. SETTING: Department of gynecology and genetics. PATIENT(S): Women with (n = 159) or without leiomyomas (n = 131). MAIN OUTCOME MEASURE(S): Polymerase chain reaction was used to detect dinucleotide (thymine-adenine [TA]) repeat polymorphisms upstream of the estrogen receptor gene. Genotypes...

Topics

Adenine
Dinucleotide Repeats
Female
Genetic Predisposition to Disease
Genotype
Humans
Leiomyoma
Polymerase Chain Reaction
Polymorphism, Genetic
Receptors, Estrogen
Thymine
Uterine Neoplasms

Source

Open in PubMed

Identifiers

PMID: 12524070
DOI: 10.1016/s0015-0282(02)04563-6

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