Down‐regulated expression of prostasin in high‐grade or hormone‐refractory human prostate cancers

Abstract excerpt

BACKGROUND: We previously conducted a search for genes which are differentially expressed in hormone-refractory prostate cancers using cDNA-representational difference analysis (RDA). The prostasin gene was isolated as one showing down-regulation in hormone-refractory cancers. In the present study, linkage to the stage in prostate neoplasia was examined. METHODS: Prostasin expressions in 54 prostate cancer cases...

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