Article
Gene expression profiling analysis of castration-resistant prostate cancer.
Medical science monitor : international medical journal of experimental and clinical research - 16 Jan 2015
Wang Xuelei, Wen Jiling, Li Rongbing, Qiu Guangming, Zhou Lan, Wen Xiaofei
Abstract excerpt
BACKGROUND: Prostate cancer is a global health issue. Usually, men with metastatic disease will progress to castration-resistant prostate cancer (CRPC). We aimed to identify the differentially expressed genes (DEGs) in tumor samples from non-castrated and castrated men from LNCaP Orthotopic xenograft models of prostate cancer and to study the mechanisms of CRPC. MATERIAL/METHODS: In this work, GSE46218 containing...
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