Article
[Frequency of donor TNF-alpha gene polymorphism in patients with graft versus host disease following hematopoietic stem cell transplantation].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2002
Wang Jing-Bo, Ren Han-Yun, Li Dan, Sun Qian, Lu Dao-Pei
Abstract excerpt
To study the effect of donor TNF-alpha gene polymorphism on severe acute and extensive chronic graft versus host disease (GVHD), TNF-alpha gene polymorphism was analyzed by denaturing high performance liquid chromatography (DHPLC) and DNA sequencing in twenty-one patients with III/IV degree acute GVHD and twenty-seven patients with extensive chronic GVHD. The results showed that the frequency of TNF-alpha-308...
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