Article
[The relationship between donor TNFalpha - 308 (G/A) genotype and recipient acute GVHD in allo-BMT].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Aug 2002
Wang Jingbo, Pan Kaifeng, Li Dan, Lu Daopei
Abstract excerpt
OBJECTIVE: To study the relationship between donor TNFalpha - 308 (G/A) genotype and recipient acute graft versus host disease (aGVHD). METHODS: TNFalpha - 308 (G/A) and TNFalpha - 308 (G/G) genotypes were analyzed by DHPLC and DNA sequence in twenty-one degree III/IV (III/IV) aGVHD patients, and twenty-eight degree 0/I (0/I) aGVHD patients. Serum TNFalpha levels were determined by ELISA. RESULTS: The frequency...
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