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Article

Inherited thrombophilic disorders in young adults with ischemic stroke and patent foramen ovale.

Stroke - 1 Jan 2003

Pezzini Alessandro, Del Zotto Elisabetta, Magoni Mauro, Costa Angelo, Archetti Silvana, Grassi Mario, Akkawi Nabil Maalikjy, Albertini Alberto, Assanelli Deodato, Vignolo Luigi Amedeo, Padovani Alessandro

Abstract excerpt

BACKGROUND AND PURPOSE: The pathogenic link between patent foramen ovale (PFO) and stroke remains unknown in most cases. We investigated the association between inherited thrombophilic disorders and PFO-related strokes in a series of young adults in the setting of a case-control study. METHODS: We investigated 125 consecutive subjects (age, 34.7+/-7.3 years) with ischemic stroke and 149 age- and sex-matched...

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Identifiers

PMID: 12511746
DOI: 10.1161/01.str.0000046457.54037.cc

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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