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Article

G1691A factor V and G20210A FII mutations, acute ischemic stroke of unknown cause, and patent foramen ovale.

Thrombosis research - 1 Nov 2012

Favaretto Elisabetta, Sartori Michelangelo, Conti Eleonora, Legnani Cristina, Palareti Gualtiero

Abstract excerpt

BACKGROUND: Genetic polymorphisms of haemostatic factors such as G1691A factor V (FV Leiden) and G20210A prothrombin (FII) may be involved in the onset of patent foramen ovale (PFO)-related cerebral ischaemia. We assessed the possible association between such inherited thrombophilic alterations and right-to-left shunt in patients with stroke. METHODS: We investigated the presence of G20210A FII and FV Leiden...

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PMID: 22909823
DOI: 10.1016/j.thromres.2012.07.020

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