Article
Factor V Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 2003
Karttunen Vesa, Hiltunen Leena, Rasi Vesa, Vahtera Elina, Hillbom Matti
Abstract excerpt
The role of paradoxical embolism through patent foramen ovale as a mechanism of cryptogenic stroke is controversial. If a venous source of emboli is relevant, prothrombotic states should be associated with patent foramen ovale and cryptogenic stroke. We assessed the occurrence of several prothrombotic states (factor V Leiden, prothrombin G20210A, deficiencies in protein S, protein C and antithrombin, lupus...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.