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[Patent foramen ovale: "les liaisons dangereuses" between anatomy and genetics].

Recenti progressi in medicina - 1 Jan 2000

Botto Nicoletta, Ait-Ali Lamia, Sicari Rosa, Spadoni Isabella, Andreassi Maria Grazia

Abstract excerpt

We reported a case of two 24-year-old and 17-year-old male patients with episode of transient ischemic attacks and diagnosed as having patent foramen ovale (PFO). One patient had heterozygosity for the factor V Leiden mutation, and one other had heterozygosity for prothrombin G20210A mutation. Both of them were also carriers for MTHFR 677T genotype with elevated plasma levels of homocysteine (22.3 +/- 3.9...

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Identifiers

PMID: 19725476

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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