Article
Association of heterozygous hemochromatosis C282Y gene mutation with hand osteoarthritis.
The Journal of rheumatology - 1 Jan 2003
Ross James M, Kowalchuk Roman M, Shaulinsky Jennifer, Ross Lori, Ryan Daniel, Phatak Pradyumna D
Abstract excerpt
OBJECTIVE: To determine if there is an association between radiographic osteoarthritis (OA) of the hand and the presence of hemochromatosis HFE gene mutations. METHODS: One hundred seventy-six patients with radiographic OA of the hand were randomly selected from an academic rheumatology practice. We measured serum transferrin saturation (TS) and ferritin levels, and genotyped for the presence of the 2 common HFE...
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