Article
Familial aggregation of psychotic symptoms in a replication set of 69 bipolar disorder pedigrees.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2003
Potash James B, Chiu Yen-Feng, MacKinnon Dean F, Miller Erin B, Simpson Sylvia G, McMahon Francis J, McInnis Melvin G, DePaulo J Raymond
Abstract excerpt
We found evidence previously of familial aggregation of psychotic symptoms in 65 bipolar disorder pedigrees. This finding, together with prior evidence from clinical, family, neurobiological, and linkage studies, suggested that psychotic bipolar disorder may delineate a valid subtype. We sought to replicate this finding in 69 new bipolar disorder pedigrees. The presence of psychotic symptoms, defined as...
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