Article
Early-onset schizophrenia and dopamine-related gene polymorphism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2003
Iwata Yasuhide, Matsumoto Hideo, Minabe Yoshio, Osada Naoko, Nakamura Kazuhiko, Sekizawa Takahiro, Suzuki Katsuaki, Sekine Yoshimoto, Takei Nori, Mori Norio
Abstract excerpt
Schizophrenic patients with an onset before age 16 years (early-onset schizophrenia, EOS) would be a rare but attractive subpopulation for genetic studies. This study explored the relationship between the polymorphism of four dopamine-regulating-enzymes (tyrosine hydroxylase, dopamine-beta-hydroxylase, catechol-O-methyltransferase, monoamine oxidase-A) genes, four dopamine-receptors (dopamine D1, D2, D3, D4...
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