[Association of DNA methyltransferase 3B gene polymorphism with early-onset schizophrenia].

doi:10.3760/cma.j.issn.1003-9406.2010.06.022

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[Association of DNA methyltransferase 3B gene polymorphism with early-onset schizophrenia].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2010

Zhang Chen, Fang Yiru, Xie Bin, Du Ya-song, Cheng Wen-hong, Wang Dong-xiang, Yu Shun-ying

Abstract excerpt

OBJECTIVE: To investigate the association of DNA methyltransferase 3B (DNMT3B) gene polymorphism with the development of early-onset schizophrenia. METHODS: A single nucleotide polymorphism (rs6119954) of DNMT3B gene was genotyped in 279 early-onset schizophrenic patients and 395 healthy controls, using TaqMan SNP Genotyping Assays. To detect the interaction between the DNMT3B gene and environmental factors, the...

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PMID: 21154337
DOI: 10.3760/cma.j.issn.1003-9406.2010.06.022

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