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Article

SarS, a SarA homolog repressible by agr, is an activator of protein A synthesis in Staphylococcus aureus.

Infection and immunity - 1 Apr 2001

Cheung A L, Schmidt K, Bateman B, Manna A C

Abstract excerpt

The expression of protein A (spa) is repressed by global regulatory loci sarA and agr. Although SarA may directly bind to the spa promoter to downregulate spa expression, the mechanism by which agr represses spa expression is not clearly understood. In searching for SarA homologs in the partially released genome, we found a SarA homolog, encoding a 250-amino-acid protein designated SarS, upstream of the spa gene....

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Share to Bacterial Proteins
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Bacterial

Share to Promoter Regions, Genetic

Share to Staphylococcal Protein A

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Source

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Identifiers

PMID: 11254606
DOI: 10.1128/IAI.69.4.2448-2455.2001
PMCID: PMC98178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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