Article
A combination of poor adherence and a low baseline susceptibility score is highly predictive for HAART failure.
Antiviral chemistry & chemotherapy - 1 Jul 2002
Van Vaerenbergh Kristien, De Geest Sabina, Derdelinckx Inge, Bobbaers Herman, Carbonez An, Deschamps Ann, De Graeve Veerle, De Saar Veerle, Ceunen Helga, De Smet Koen, Maes Bart, Peetermans Willy, Schrooten Yoeri, Desmyter Jan, De Clercq Erik, Van Ranst Marc, Van Wijngaerden Eric, Vandamme Anne-Mieke
Abstract excerpt
The relationship between adherence, virological response to highly active antiretroviral therapy (HAART) and the presence and development of genotypic resistance was assessed in 41 HIV-infected patients on HAART. Four adherence parameters (drug taking adherence, dosing adherence, timing adherence and drug holidays) were scored prospectively using electronic event monitoring. Genotypic resistance at baseline and...
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