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Article

Linezolid resistance in clinical isolates of Staphylococcus aureus

12 Dec 2002

Abstract excerpt

Sir, Linezolid is the first oxazolidinone antibiotic to be licensed for treatment of Gram-positive infections. It is active against methicillin-resistant Staphylococcus aureus (MRSA), glycopeptide-intermediate S. aureus (GISA) and vancomycin-resistant enterococci (VRE).1 It inhibits the formation of the initiation complex formed with mRNA, fMet-tRNA and the 30S ribosomal subunit. Mutations to the central loop of...

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PMID: 12493812
DOI: 10.1093/jac/dkg104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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