Article
Genetics of the immune response: identifying immune variation within the MHC and throughout the genome.
Immunological reviews - 1 Dec 2002
Geraghty Daniel E, Daza Riza, Williams Luke M, Vu Quyen, Ishitani Akiko
Abstract excerpt
With the advent of modern genomic sequencing technology the ability to obtain new sequence data and to acquire allelic polymorphism data from a broad range of samples has become routine. In this regard, our investigations have started with the most polymorphic of genetic regions fundamental to the immune response in the major histocompatibility complex (MHC). Starting with the completed human MHC genomic...
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