Article
Somatic cell mutations at the glycophorin a locus in erythrocytes of radiation workers from the Sellafield nuclear facility.
Radiation research - 1 Jan 2003
Janet Tawn E, Whitehouse Caroline A, Paul Daniel C, Tarone Robert E, Bothwell Andrea M, Fisher Ann
Abstract excerpt
The glycophorin A (GPA) somatic mutation assay for N0 and NN mutant erythrocytes was performed on 245 current and 48 retired workers who had been occupationally exposed to radiation at the British Nuclear Fuels plc facility at Sellafield. A positive association with increasing age was found for current workers for both N0 and NN frequencies of 0.14 +/- 0.05 x 10(-6) (P = 0.012) and 0.25 +/- 0.07 x 10(-6) (P =...
Topics
- Adolescent
- Adult
- Aging
- Erythrocytes
- Glycophorins
- Humans
- Middle Aged
- Mutation
- Occupational Exposure
- Power Plants
- Retirement
- Smoking
- United Kingdom
