Article
Lac z Histochemistry and immunohistochemistry reveal ephrin-B ligand expression in the inner ear.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Dec 2002
Bianchi Lynne M, Dinsio Kyl, Davoli Katherine, Gale Nicholas W
Abstract excerpt
Immunostaining in transgenic mice carrying the lac z gene can be used to map gene and protein distribution in a single tissue. In this study, we examined inner ears from ephrin-B3 homozygous and ephrin-B2 heterozygous mice. Ephrin-B3 lac z expression was limited in these mice. However, immunostaining revealed ephrin-B3 throughout cochlear and vestibular regions. Immunoreactivity was absent in ephrin-B3-homozygous...
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