Article
Transforming growth factor-beta expression in cardiovascular organs in stroke-prone spontaneously hypertensive rats with the development of hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Nov 2002
Tahira Yoshiko, Fukuda Noboru, Endo Morito, Suzuki Ryo, Ikeda Yukihiro, Takagi Hiroto, Matsumoto Koichi, Kanmatsuse Katsuo
Abstract excerpt
Transforming growth factor (TGF)-beta activity is involved in several cardiovascular diseases owing to its effects on the growth of vascular smooth muscle cells and induction of extracellular matrix formation. We evaluated expression of TGF-beta in cardiovascular organs from stroke-prone spontaneously hypertensive rats (SHR-SP) which show severe cardiovascular damages with the development of hypertension....
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