Article
The K121Q polymorphism in the plasma cell membrane glycoprotein 1 gene predisposes to early myocardial infarction.
Journal of molecular medicine (Berlin, Germany) - 1 Dec 2002
Endler Georg, Mannhalter Christine, Sunder-Plassmann Heike, Schillinger Martin, Klimesch Alexandra, Exner Markus, Kapiotis Sonja, Meier Susanne, Kunz Freja, Raiger Elisabeth, Huber Kurt, Wagner Oswald, Sunder-Plassmann Raute
Abstract excerpt
Elevated plasma cell membrane glycoprotein 1 (PC-1) expression and the frequent PC-1 K121Q polymorphism have recently been associated with insulin resistance. Since insulin resistance represents an important risk factor for atherosclerotic vascular disease and myocardial infarction, we investigated the involvement of the PC-1 K121Q polymorphism in the development of myocardial infarction. We analyzed two...
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