Article
Chitotriosidase deficiency in survivors of Candida sepsis.
Blood cells, molecules & diseases - 1 Jan 2000
Masoud M, Rudensky B, Elstein D, Zimran A
Abstract excerpt
The existence of chitotriosidase, a human chitinolytic enzyme, hydrolyzes artificial chitotrioside substrates, but its specific function in humans is unknown. The homologous chitinases have an anti-fungal action in plants. In patients with Gaucher disease, chitotriosidase activity is markedly elevated and is a marker for response to specific treatment. In all populations, 6% of individuals are enzyme deficient...
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