Article
The human chitotriosidase gene. Nature of inherited enzyme deficiency.
The Journal of biological chemistry - 2 Oct 1998
Boot R G, Renkema G H, Verhoek M, Strijland A, Bliek J, de Meulemeester T M, Mannens M M, Aerts J M
Abstract excerpt
The human chitinase, named chitotriosidase, is a member of family 18 of glycosylhydrolases. Following the cloning of the chitotriosidase cDNA (Boot, R. G., Renkema, G. H., Strijland, A., van Zonneveld, A. J., and Aerts, J. M. F. G. (1995) J. Biol. Chem. 270, 26252-26256), the gene and mRNA have b...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Cloning, Molecular
- DNA Mutational Analysis
- Genotype
- Hexosaminidases
- Homozygote
- Humans
- In Situ Hybridization
- Macrophages
- Molecular Sequence Data
- Netherlands
- RNA, Messenger
- Repetitive Sequences, Nucleic Acid
- Sequence Analysis, DNA
- Sequence Deletion