Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microsatellite instability in hematological malignancies.

Leukemia & lymphoma - 1 Oct 2002

Krsková-Honzátková Lenka, Cermák Jaroslav, Sajdová Jana, Starý Jan, Sedlácek Petr, Sieglová Zuzana

Abstract excerpt

The replication error (RER+) phenotype, characterized by microsatellite instability (MSI) has been recently related to mutations of genes involved in DNA mismatch repair pathway. These genetic alterations were first described in hereditary non polyposis colorectal cancer (HNPCC). We examined 44 patients with hematological malignancies (27 AML, 9 MDS, 2 CML-BP and 6 T-ALL) for evidence of MSI. Twenty seven percent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Trinucleotide Repeat Expansion
Share to DNA Repair
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematologic Neoplasms

Share to Infant

Share to Loss of Heterozygosity

Share to Microsatellite Repeats

Share to Recurrence

Source

Identifiers

PMID: 12481896
DOI: 10.1080/1042819021000015835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microsatellite instability in hematological malignancies.PMID 12481896Read ↗

Genetic instability in human mismatch repair deficient cancers.Semantic proximity Read ↗

Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables.Semantic proximity Read ↗

[What's new about microsatellite instability significance in human carcinogenesis?].Semantic proximity Read ↗

[Clinical and molecular consequences of microsatellite instability in human cancers].Semantic proximity Read ↗

Microsatellite instability in primary and metastatic colorectal cancers.Semantic proximity Read ↗

Genetic instability of microsatellites in hematological neoplasms.Semantic proximity Read ↗

Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas.Semantic proximity Read ↗

Microsatellite instability in childhood rhabdomyosarcoma is locus specific and correlates with fractional allelic loss.Semantic proximity Read ↗

Mutations of E2F-4 trinucleotide repeats in colorectal cancer with microsatellite instability.Semantic proximity Read ↗

Replication errors in hematological neoplasias: genomic instability in progression of disease is different among different types of leukemia.Semantic proximity Read ↗

Microsatellite instability in endometrial carcinoma.Semantic proximity Read ↗

Genomic instability in colorectal cancers in Turkey.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.