Article
Polymorphic genes for kinin receptors, nephropathy and blood pressure in type 2 diabetic patients.
American journal of nephrology - 1 Jan 2000
Zychma Marcin J, Gumprecht Janusz, Trautsolt Wanda, Szydlowska Ilona, Grzeszczak Wladyslaw
Abstract excerpt
BACKGROUND/AIMS: There is evidence that hereditary predisposition contributes to the development of diabetic nephropathy and hypertension. Polymorphisms in the genes for bradykinin receptors (B(1)R and B(2)R) were found to be associated with decreased risk of the development of end-stage renal disease. This study examines whether B(1)R G(-699)C and B(2)R C(181)T polymorphisms are associated with microalbuminuria...
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