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Article

Platelet-activating factor and Escherichia coliO157:H7 infections.

Pediatric nephrology (Berlin, Germany) - 1 Dec 2002

Smith Jodi M, Jones Falaah, Ciol Marcia A, Jelacic Srdjan, Boster Daniel R, Watkins Sandra L, Williams Glyn D, Tarr Phillip I, Henderson William R

Abstract excerpt

The role of platelet-activating factor (PAF), a phospholipid inflammatory mediator, in Escherichia coli O157:H7-associated hemolytic uremic syndrome (HUS) is unknown. PAF is synthesized by diverse cells and is degraded by PAF-acetylhydrolase (PAF-AH). Deficient PAF-AH activity results from a G-->T transversion at position 994 of exon 9. We examined children infected with E. coliO157:H7 to determine if PAF levels...

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Identifiers

PMID: 12478356
DOI: 10.1007/s00467-002-0970-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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