Article
[The relationship between haplotypes of angiotensinogen gene and essential hypertension].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2002
Kong Xiangdong, Zhang Sizhong, Yang Yuxia, Zheng Keqin, Tong Yu, Shi Jiajun, Zhang Kelan, Su Zhiguang, Cheng Wei
Abstract excerpt
OBJECTIVE: To investigate the relationship between the polymorphism of angiotensinogen gene (AGT) and the risk for hypertension in a Chinese population. METHODS: Three polymorphisms of AGT gene were analyzed in 335 patients with documented essential hypertension and 196 control subjects by using PCR-restriction fragment length polymorphism. Expectation maximization(EM) algorithm was then used for pairwise linkage...
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