Article
[The relationship between the variants in 5' upstream core promoter A(-6)G and A(-20)C of angiotensinogen gene and essential hypertension in Kazakans of Xinjiang].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2004
Li Nan-fang, Zhou Ling, Wu Wei-dong, Shi Yan, Wang Xin-ling, Wang Jun, Li Hong-jian, Zhang De-lian, Zu Here, Ouyang Wei-jin, Bu Ke-li, Zhou Ke-ming, Cheng Qiu-yan, Guli Nur, Zhu Deng-hao
Abstract excerpt
OBJECTIVE: To investigate whether the variants A(-6)G and A(-20)C of angiotensinogen (AGT) gene are involved in the pathogenesis of essential hypertension in Kazakans. METHODS: T his case control study recruited 125 subjects with hypertension and 74 normotensive subjects from Kazakans of Xinjiang. Genomic DNA from leukocytes was analyzed for genetic variants A(-6)G and A(-20)C in 5' upstream core promoter of AGT...
Topics
- 5' Flanking Region
- Adult
- Alleles
- Angiotensinogen
- Base Sequence
- Blood Pressure
- Case-Control Studies
- China
- DNA