Article
[Relationship between six single nucleotide polymorphisms of angiotensinogen gene and essential hypertension].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2004
Liu Yan, Jin Wei, Jiang Zheng-wen, Zhang Kui-xing, Sheng Hai-hui, Jin Lin, Sheng Ya-yun, Huang Wei, Yu Jin-de
Abstract excerpt
OBJECTIVE: To evaluate the relationship of six single nucleotide polymorphisms(SNPs) and their haplotypes of angiotensinogen(AGT) gene to essential hypertension(EH) in Chinese Han population. METHODS: The genotypes in 185 patients with EH and 185 healthy controls were determined by the method of ABI PRISM SNaPshot Multiplex Kit using six AGT gene polymorphisms at position -217(G/A), -152(G/A), -20(A/C) and...
Topics
- Adult
- Aged
- Angiotensinogen
- Female
- Haplotypes
- Humans
- Hypertension
- Male
- Middle Aged
- Polymorphism, Single Nucleotide