Article
Nine polymorphisms of angiotensinogen gene in the susceptibility to essential hypertension.
Life sciences - 8 Dec 2000
Sato N, Katsuya T, Nakagawa T, Ishikawa K, Fu Y, Asai T, Fukuda M, Suzuki F, Nakamura Y, Higaki J, Ogihara T
Abstract excerpt
Even if the importance of angiotensinogen (AGT) gene has been known in gene targeting animals and humans genetic studies, its precise mechanism and the interaction among AGT gene variants, plasma AGT concentration and risk for hypertension remain uncertain. We examined whether AGT gene variants predispose to hypertension via an increase of plasma AGT concentration. Plasma AGT concentration was estimated from...
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