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Article

Mutation theory of aging, assessed in transgenic mice and knockout mice.

Mechanisms of ageing and development - 1 Nov 2002

Ono Tetsuya, Uehara Yoshihiko, Saito Yusuke, Ikehata Hironobu

Abstract excerpt

A vital question in the mutation theory of aging is whether mutation accumulates with age. If it does, what are the causes and consequences of the accumulation of mutation? The recent development of transgenic mice has made it possible to study mutation in different kinds of tissues and at a mole...

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PMID: 12470892
DOI: 10.1016/s0047-6374(02)00090-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12470892-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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