Article
Dopamine modulation of avoidance behavior in Caenorhabditis elegans requires the NMDA receptor NMR-1.
PloS one - 1 Jan 2014
Baidya Melvin, Genovez Marx, Torres Marissa, Chao Michael Y
Abstract excerpt
The nematode C. elegans utilizes a relatively simple neural circuit to mediate avoidance responses to noxious stimuli such as the volatile odorant octanol. This avoidance behavior is modulated by dopamine. cat-2 mutant animals that are deficient in dopamine biosynthesis have an increased response latency to octanol compared to wild type animals, and this defect can be fully restored with the application of...
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