Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human models of aromatase deficiency.

The Journal of steroid biochemistry and molecular biology - 1 Apr 2008

Zirilli Lucia, Rochira Vincenzo, Diazzi Chiara, Caffagni Giovanni, Carani Cesare

Abstract excerpt

Estrogens exert a wide range of biological effects in both sexes also on non-reproductive systems and organs. Human congenital estrogen deficiency, due to an inactivating mutation of the aromatase gene, leads to the lack of the estrogen synthesis, with gonadotropins and circulating testosterone r...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice, Knockout
Share to Infant, Newborn
Share to Metabolic Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aromatase

Share to Bone Density

Share to Estrogens

Share to Glycolipids

Share to Models, Biological

Source

Identifiers

PMID: 18448329
DOI: 10.1016/j.jsbmb.2008.03.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18448329-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human models of aromatase deficiency.PMID 18448329Read ↗

Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men.Semantic proximity Read ↗

Pediatric endocrinology update: an overview. The essential roles of estrogens in pubertal growth, epiphyseal fusion and bone turnover: lessons from mutations in the genes for aromatase and the estrogen receptor.Semantic proximity Read ↗

Clinical review 78: Aromatase deficiency in women and men: would you have predicted the phenotypes?Semantic proximity Read ↗

Of mice and men: the evolving phenotype of aromatase deficiency.Semantic proximity Read ↗

A novel mutation in the human aromatase gene: insights on the relationship among serum estradiol, longitudinal growth and bone mineral density in an adult man under estrogen replacement treatment.Semantic proximity Read ↗

Bone Disease Associated with Inactivating Aromatase Mutations and its Management.Semantic proximity Read ↗

Recognizing rare disorders: aromatase deficiency.Semantic proximity Read ↗

[Estrogen resistance and aromatase deficiency in humans].Semantic proximity Read ↗

Estrogen: consequences and implications of human mutations in synthesis and action.Semantic proximity Read ↗

Aromatase deficiency and estrogen resistance: from molecular genetics to clinic.Semantic proximity Read ↗

Congenital estrogen deficiency: in search of the estrogen role in human male reproduction.Semantic proximity Read ↗

Effect of estrogen deficiency in the male: the ArKO mouse model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.