Article
p53 codon 72 polymorphism and risk of cervical cancer in UK.
Lancet (London, England) - 12 Sept 1998
Rosenthal A N, Ryan A, Al-Jehani R M, Storey A, Harwood C A, Jacobs I J
Abstract excerpt
BACKGROUND: A polymorphism at codon 72 of the human tumour-suppressor gene, p53, results in translation to either arginine or proline. A recent report suggested that the risk of human-papillomavirus-associated cervical cancer in white women is higher for those homozygous for the arginine allele t...
Topics
- Amino Acid Sequence
- Arginine
- Carcinoma, Squamous Cell
- Codon
- Disease Susceptibility
- Female
- Genes, p53
- Genotype
- Heterozygote
- Homozygote
- Humans
- Polymorphism, Genetic
- Proline
- Risk Factors
- United Kingdom
- Uterine Cervical Neoplasms