Article
Presence of hepatitis B surface antigen mutant G145R DNA in the peripheral blood leukocytes of the family members of an asymptomatic carrier and evidence of its horizontal transmission.
Virus research - 1 Dec 2002
Chakravarty Runu, Neogi Madhubanti, Roychowdhury Susanta, Panda Chinmoy Kumar
Abstract excerpt
An asymptomatic carrier and all six of his family members were detected positive for HBV DNA in their peripheral blood leukocytes (PBL), by polymerase chain reaction. Direct sequencing of the amplified DNA revealed that the HBV DNA from the carrier and his wife was of subtype ayw. Interestingly, the amplified HBV DNA from the five other members of the family was found to be not only of subtype adw but also...
Topics
- Adult
- Aged
- Carrier State
- DNA, Viral
- Disease Transmission, Infectious
- Family Health
- Female
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Surface Antigens
- Hepatitis B virus