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Article

Identification and characterization of mutations in 'X' region of a hepatitis B virus carrier.

Indian journal of biochemistry & biophysics - 1 Dec 1992

Banerjee K, Khandekar P

Abstract excerpt

A defective form of Hepatitis B virus (HBV) was identified in an apparently healthy voluntary blood donor, who was positive for the presence of HBV by dot blot hybridization, but did not have any serological markers of HBV infection. Two regions, part of X and part of surface antigen genes, were amplified by polymerase chain reaction, cloned and sequenced by Sanger's dideoxy chain termination method. The base...

Topics

Amino Acid Sequence
Base Sequence
Blood Donors
Carrier State
Cloning, Molecular
DNA, Viral
Hepatitis B virus
Humans
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Restriction Mapping

Source

Identifiers

PMID: 1294468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1294468-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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