Article
TupA, the Penicillium marneffei Tup1p homologue, represses both yeast and spore development.
Molecular microbiology - 1 Apr 2003
Todd Richard B, Greenhalgh Jennifer R, Hynes Michael J, Andrianopoulos Alex
Abstract excerpt
Fungal pathogenesis is frequently associated with dimorphism - morphological changes between yeast and filamentous forms. Penicillium marneffei, an opportunistic human pathogen, exhibits temperature-dependent dimorphism, with growth at 25 degrees C as filamentous multinucleate hyphae switching at 37 degrees C to uninucleate yeast cells associated with intracellular pathogenesis. The filamentous hyphae also...
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