Article
The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development.
The EMBO journal - 1 Oct 1996
Yu J H, Wieser J, Adams T H
Abstract excerpt
flbA encodes an Aspergillus nidulans RGS (regulator of G protein signaling) domain protein that is required for control of mycelial proliferation and activation of asexual sporulation. We identified a dominant mutation in a second gene, fadA, that resulted in a very similar phenotype to flbA loss...
Topics
- Amino Acid Sequence
- Aspergillus nidulans
- Cell Division
- Cloning, Molecular
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Phenotype
- Restriction Mapping
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Signal Transduction
- Spores, Fungal
- Suppression, Genetic