Article

Frameshift mutations of <i>YPEL3</i> alter sensory circuit function in <i>Drosophila</i>

2019-09-13

Abstract excerpt

<h4>ABSTRACT</h4> A frameshift mutation in Yippee-like ( YPEL) 3 was recently found from a rare human disorder with peripheral neurological conditions including hypotonia and areflexia. The YPEL gene family is highly conserved from yeast to human, but their functions are poorly defined. Moreover, the pathogenicity of the human YPEL3 variant is completely unknown. To tackle these issues, we generated a Drosop...

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Literature Corpus work: d1fefb55-8f74-5356-972e-a669b50ddcb9
DOI: 10.1101/768358

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