Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The prevalence of the HNF-1alpha G319S mutation in Canadian aboriginal youth with type 2 diabetes.

Diabetes care - 1 Dec 2002

Sellers Elizabeth A C, Triggs-Raine Barbara, Rockman-Greenberg Cheryl, Dean Heather J

Abstract excerpt

OBJECTIVE: To investigate the prevalence of the unique HNF-1alpha G319S mutation in a population of aboriginal youth with type 2 diabetes and to describe the relationship between clinical and historical characteristics and the presence or absence of the HNF-1alpha G319S mutation. RESEARCH DESIGN AND METHODS: Participating youth were genotyped for the G319S mutation of the HNF-1alpha gene. Clinical, laboratory,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to American Indian or Alaska Native
Share to Amino Acid Substitution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Canada

Share to Diabetes Mellitus, Type 2

Share to Hepatocyte Nuclear Factor 1

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Hepatocyte Nuclear Factor 1-beta

Share to Mutation, Missense

Source

Identifiers

PMID: 12453961
DOI: 10.2337/diacare.25.12.2202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The prevalence of the HNF-1alpha G319S mutation in Canadian aboriginal youth with type 2 diabetes.PMID 12453961Read ↗

The hepatic nuclear factor-1alpha G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree.Semantic proximity Read ↗

Exploring the role of the HNF-1αG319S polymorphism in β cell failure and youth-onset type 2 diabetes: Lessons from MODY and Hnf-1α-deficient animal models.Semantic proximity Read ↗

Clinical utility of HNF1A genotyping for diabetes in aboriginal Canadians.Semantic proximity Read ↗

The Metabolic Phenotype of Youth Onset Type 2 Diabetes: The Role of Pregestational Diabetes Exposure and the Hepatic Nuclear Factor 1Alpha G319S Polymorphism.Semantic proximity Read ↗

Genes, environment and Oji-Cree type 2 diabetes.Semantic proximity Read ↗

Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study.Semantic proximity Read ↗

HNF-1alpha G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community.Semantic proximity Read ↗

Diabetes susceptibility in the Canadian Oji-Cree population is moderated by abnormal mRNA processing of HNF1A G319S transcripts.Semantic proximity Read ↗

Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.Semantic proximity Read ↗

[HNF-1alpha G319S mutation in Oji-Cree type 2 diabetes].Semantic proximity Read ↗

A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.Semantic proximity Read ↗

Genetics and type 2 diabetes in youth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.