Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren's syndrome.

Arthritis research - 1 Jan 2002

Dörner Thomas, Lipsky Peter E

Abstract excerpt

Primary Sjögren's syndrome (pSS) is an autoimmune disorder characterized by specific pathologic features and the production of typical autoantibodies. In addition, characteristic changes in the distribution of peripheral B cell subsets and differences in use of immunoglobulin variable-region genes are also features of pSS. Comparison of B cells from the blood and parotid gland of patients with pSS with those of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmunity
Share to B-Lymphocytes
Share to Gene Expression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to Phenotype

Share to Sjogren's Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 12453312
DOI: 10.1186/ar603
PMCID: PMC153845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren's syndrome.PMID 12453312Read ↗

Ig Gene Analysis Reveals Altered Selective Pressures on Ig-Producing Cells in Parotid Glands of Primary Sjögren’s Syndrome PatientsSemantic proximity Read ↗

B cells in Sjögren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissueSemantic proximity Read ↗

B cells in the pathogenesis of primary Sjögren syndrome.Semantic proximity Read ↗

Diminished peripheral blood memory B cells and accumulation of memory B cells in the salivary glands of patients with Sjögren's syndrome.Semantic proximity Read ↗

Current views on the pathogenesis of Sjögren's syndrome.Semantic proximity Read ↗

CD8+ T Lymphocytes: Crucial Players in Sjögren's Syndrome.Semantic proximity Read ↗

Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren’s syndromeSemantic proximity Read ↗

Primary Sjogren’s Syndrome and the Type I Interferon SystemSemantic proximity Read ↗

Unique Phenotypes and Functions of Follicular Helper T Cells and Regulatory T Cells in Sjögren's Syndrome.Semantic proximity Read ↗

Multimodal Single-Cell Sequencing of B Cells in Primary Sjögren's Syndrome.Semantic proximity Read ↗

Primary Sjögren's Syndrome Is Characterized by Distinct Phenotypic and Transcriptional Profiles of IgD+ Unswitched Memory B CellsSemantic proximity Read ↗

Reduced circulating regulatory T cells in primary Sjögren’s syndrome: the contribution of enhanced apoptosis and impaired survivalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.