Article
Unique Phenotypes and Functions of Follicular Helper T Cells and Regulatory T Cells in Sjögren's Syndrome.
Current rheumatology reviews - 1 Jan 2018
Saito Masako, Otsuka Kunihiro, Ushio Aya, Yamada Akiko, Arakaki Rieko, Kudo Yasusei, Ishimaru Naozumi
Abstract excerpt
Sjogren's syndrome (SS) is a T cell-mediated autoimmune disease of the systemic exocrine glands, such as salivary and lacrimal glands. A variety of T-cell subpopulations maintain immune tolerance in the thymus and periphery through complex immune responses including cellular and humoral immunity. The T-cell subpopulations exhibiting abnormal or unique phenotypes and impaired functionality have been reported to...
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