Article
Induction and Regulation of Endogenous Granulocyte Colony-Stimulating Factor Formation
6 Jan 2002
Abstract excerpt
Granulocyte colony-stimulating factor (G-CSF) is one of the most prominent endogenous proteins in broad clinical use. While its biological and clinical effects are relatively well studied, little is known about its endogenous formation in health and disease. However, such knowledge is crucial to decide in which situations G-CSF should be applied efficiently in the clinic, ie. when endogenous production does not...
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