Article
Influence of cytokine genes polymorphisms on long-term outcome in renal transplantation.
Clinical transplantation - 1 Jan 2000
Breulmann Bärbel, Bantis Christos, Siekierka Magdalena, Blume Cornelia, Aker Sendogan, Kuhr Nicola, Grabensee Bernd, Ivens Katrin
Abstract excerpt
BACKGROUND: Recently, polymorphisms of cytokine genes have been associated with modified gene expression and increased cytokine production. We evaluated the influence of interleukin-10 (IL-10) gene G-1082A, tumour necrosis factor alpha (TNFalpha) gene G-308A and IL-6 gene G-174C polymorphisms on the rejection rate, renal function and long-term outcome in renal transplantation. PATIENTS AND METHODS: We studied n =...
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