Article
Identification of a new segment involved in cagA 3' region variation of Helicobacter pylori.
FEMS immunology and medical microbiology - 25 Mar 2002
Dong Quanjiang, O'Sullivan Maria, Hall Wendy, Herra Celine, Kean Conor, O'Morain Colm, Buckley Martin
Abstract excerpt
The cagA 3' region shows marked variation among Helicobacter pylori strains. Two segments of 102 bp and 57 bp are reportedly responsible for this variation. We analysed the cagA 3' region in 70 H. pylori strains using polymerase chain reaction and sequencing. We found that another segment, namely...
Topics
- Amino Acid Sequence
- Antigens, Bacterial
- Bacterial Proteins
- Duodenal Ulcer
- Gastritis
- Genes, Bacterial
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Ireland
- Metaplasia
- Molecular Epidemiology
- Molecular Sequence Data
- Phosphorylation
- Phosphotyrosine
- Polymerase Chain Reaction
- Protein Processing, Post-Translational