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Identification of a new segment involved in cagA 3' region variation of Helicobacter pylori.

FEMS immunology and medical microbiology - 25 Mar 2002

Dong Quanjiang, O'Sullivan Maria, Hall Wendy, Herra Celine, Kean Conor, O'Morain Colm, Buckley Martin

Abstract excerpt

The cagA 3' region shows marked variation among Helicobacter pylori strains. Two segments of 102 bp and 57 bp are reportedly responsible for this variation. We analysed the cagA 3' region in 70 H. pylori strains using polymerase chain reaction and sequencing. We found that another segment, namely beta segment, was also involved in the variation of this region. The beta segment was 105 bp long and located between...

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PMID: 11985969
DOI: 10.1111/j.1574-695X.2002.tb00572.x

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