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Article

Mutations of Fas (APO-1/CD95) and p53 genes in nonmelanoma skin cancer.

Journal of cutaneous medicine and surgery - 1 Jan 2000

Boldrini Laura, Loggini Barbara, Gisfredi Silvia, Zucconi Ylenia, Baldinotti Fulvia, Fogli Antonella, Simi Paolo, Cervadoro Gregorio, Barachini Paolo, Basolo Fulvio, Pingitore Raffaele, Fontanini Gabriella

Abstract excerpt

BACKGROUND: There is considerable evidence that apoptosis plays an important role in the pathogenesis of a wide variety of skin diseases. Apoptosis failure may ensure the survival of transformed cells prone to sustain further genetic damage and it plays an important part in the development of tumors. Genetic alterations of Fas and p53, with consequent inactivation of gene protein products, may be involved in...

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Identifiers

PMID: 12447615
DOI: 10.1007/s10227-002-0105-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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