Apoptosis: escaping strategies in human skin cancer (Review).

Abstract excerpt

Apoptosis must be considered a rescue mechanism that controls the integrity of the cell erasing aberrant clones and it is likely that failure of apoptosis constitutes a key factor responsible for tumour formation, progression and resistance to drugs. Several genes (e.g. survivin, bcl-2 family, p53) are involved in these pathways. Much work still needs to be done to identify the molecular pathway of apoptosis...

Topics

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• Apoptosis
• Disease Progression
• Genes, p53
• Mutation
• Skin Neoplasms