Reduced Positive Selection in Vector-Borne RNA Viruses

Abstract excerpt

RNA viruses evolve at greatly elevated rates compared with their DNA counterparts. This is principally due to the high mutation rate associated with RNA polymerase, which introduces approximately one error per genome during each round of viral replication, a rate some two orders of magnitude higher than observed in DNA viruses (Drake et al. 1998 ). The potential for rapid evolutionary change is thought to provide...

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