Article
IgE autoantibodies and their association with the disease activity and phenotype in bullous pemphigoid: a systematic review.
Archives of dermatological research - 1 Jan 2018
Saniklidou Ariadne Hadjikyriacou, Tighe Patrick J, Fairclough Lucy C, Todd Ian
Abstract excerpt
Bullous pemphigoid (BP) is the most common autoimmune skin disease of blistering character. The underlying pathophysiological mechanism involves an immune attack, usually by IgG class autoantibodies, on the autoantigen BP 180/BPAg2, which is a type XVII collagen (COL17) protein acting as the adhesion molecule between the epidermis and the basement membrane of the dermis. About 40 years ago, following consistent...
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