Article
The role of antibody class and target on subepidermal blistering disease phenotype and management.
Italian journal of dermatology and venereology - 1 Jun 2026
Lambert Raphaella A, Noot Christiaan H, Frost Zachary, Ney Zachary C, Hansen Annika M, Ahmed Areeba, Verma Hannah, Rabinowitz Grace, Gulati Nicholas, Sreekantaswamy Shreya, Zone John J, Rhoads Jamie L, Hull Christopher, Adalsteinsson Jonas A, Hopkins Zachary H
Abstract excerpt
Subepidermal blistering diseases are driven by autoantibodies targeted to the basement membrane zone. These autoantibodies can stem from multiple antibody classes (e.g., IgE, IgG, IgM, IgA) and differing antibody classes and antibody targets can impact disease phenotype and potentially management. Despite significant advances, there remains a paucity of data and funding for further elucidating subepidermal...
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